Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
939 2 |
Ultima descărcare din IBN: 2020-03-22 15:54 |
SM ISO690:2012 LUPAŞCU-VOLENTIR, Felicia, GROPPA, Liliana, BARBACAR, Nicolae, LUPAŞCU, Galina. Studii clinice şi genetico-moleculare cu privire la boala mixtă a ţesutului conjunctiv
. In: Curierul Medical, 2009, nr. 2 (308), pp. 14-19. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 2 (308) / 2009 / ISSN 1875-0666 | ||||||
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Pag. 14-19 | ||||||
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Clinical and Genetic-Molecular Research Regarding Connective Tissue Disease
The article presents research on two related topics: 1) connective tissue disease, manifested in the articular modification and in the condition
of the joints themselves, and in clinical observation, and, 2) polymorphism in DNA fragments (PCR analyses) of the genes controlling synthesis
cytokines - IL 1, IL 6 and CTLA 4. Clusterian analyses revealed the degree of relationship between joint and extrajoint clinical manifestation and
the gene mutations from a sample of mixed connective tissue disease patients. These were contrasted with a control sample of patients suffering
from i.e., systemic lupus erythematosus, systemic sclerosis and rheumatoid arthritis.
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Cuvinte-cheie connective tissue disease |
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