Substituted 1,3-phenyl(pyridyl) propenones and derivatives with thiosemicarbazidic groups. Structrure – (hl-60) antileukemia activity relationship
Închide
Conţinutul numărului revistei
Articolul precedent
Articolul urmator
398 4
Ultima descărcare din IBN:
2019-11-04 10:38
Căutarea după subiecte
similare conform CZU
[547+544+579.61]:615.12 (1)
Chimie organică (210)
Chimie fizică (275)
Microbiologie aplicată (175)
Farmacia în general şi profesia de farmacist (106)
SM ISO690:2012
POPUSHOI, Ana; GULEA, Aurelian; BARBA, Nicanor; ROY, Jenny; POIRIER, Donald. Substituted 1,3-phenyl(pyridyl) propenones and derivatives with thiosemicarbazidic groups. Structrure – (hl-60) antileukemia activity relationship. In: Chemistry Journal of Moldova. 2014, nr. 2(9), pp. 67-73. ISSN 1857-1727.
10.19261/cjm.2014.09(2).10
EXPORT metadate:
Google Scholar
Crossref
CERIF
BibTeX
DataCite
Dublin Core
Chemistry Journal of Moldova
Numărul 2(9) / 2014 / ISSN 1857-1727 /ISSNe 2345-1688

Substituted 1,3-phenyl(pyridyl) propenones and derivatives with thiosemicarbazidic groups. Structrure – (hl-60) antileukemia activity relationship

CZU: [547+544+579.61]:615.12
DOI: 10.19261/cjm.2014.09(2).10
Pag. 67-73

Popushoi Ana1, Gulea Aurelian1, Barba Nicanor1, Roy Jenny2, Poirier Donald2
 
1 State University of Moldova,
2 CHUL Research Center (Université Laval)
 
Proiect:
INTAS 2004-78-7193 Imaging GaAs X-ray Detectors
 
Disponibil în IBN: 27 martie 2017


Rezumat

3-(4-(Dimethylamino)phenyl-1-(4-isothiocyanatophenyl)prop-2-en-1-one was obtained from the corresponding N,N-dimethylthyoureas by elimination of dimethylamine at heating with gaseous hydrogen chloride in chloroform and 1-(4-isothiocyanatophenyl)-3-(pyridin-2-il)prop-2-en-1-one by treating 1,1-dimethyl-3-(4-(3-(pyridin-2-il)-acryloyl)-phenyl)thyourea with acetic anhydride. For all obtained compounds in the course of reaction the antileukemia activity was investigated

Cuvinte-cheie
chalcones, isothiocyanatopropenones, thioureas, antileukemia activity

DataCite XML Export

<?xml version='1.0' encoding='utf-8'?>
<resource xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xmlns='http://datacite.org/schema/kernel-3' xsi:schemaLocation='http://datacite.org/schema/kernel-3 http://schema.datacite.org/meta/kernel-3/metadata.xsd'>
<identifier identifierType='DOI'>10.19261/cjm.2014.09(2).10</identifier>
<creators>
<creator>
<creatorName>Popuşoi, A.</creatorName>
<affiliation>Universitatea de Stat din Moldova, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Gulea, A.P.</creatorName>
<affiliation>Universitatea de Stat din Moldova, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Barbă, N.</creatorName>
<affiliation>Universitatea de Stat din Moldova, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Roy, J.</creatorName>
<affiliation>CHUL Research Center  (Université Laval), Canada</affiliation>
</creator>
<creator>
<creatorName>Poirier, D.</creatorName>
<affiliation>CHUL Research Center  (Université Laval), Canada</affiliation>
</creator>
</creators>
<titles>
<title xml:lang='en'>Substituted 1,3-phenyl(pyridyl) propenones and derivatives with thiosemicarbazidic groups. Structrure – (hl-60) antileukemia activity relationship</title>
</titles>
<publisher>Instrumentul Bibliometric National</publisher>
<publicationYear>2014</publicationYear>
<relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>1857-1727</relatedIdentifier>
<subjects>
<subject>chalcones</subject>
<subject>isothiocyanatopropenones</subject>
<subject>thioureas</subject>
<subject>antileukemia activity</subject>
<subject schemeURI='http://udcdata.info/' subjectScheme='UDC'>[547+544+579.61]:615.12</subject>
</subjects>
<dates>
<date dateType='Issued'>2014-01-01</date>
</dates>
<resourceType resourceTypeGeneral='Text'>Journal article</resourceType>
<descriptions>
<description xml:lang='en' descriptionType='Abstract'>3-(4-(Dimethylamino)phenyl-1-(4-isothiocyanatophenyl)prop-2-en-1-one was obtained from the corresponding N,N-dimethylthyoureas by elimination of dimethylamine at heating with gaseous hydrogen chloride in chloroform and 1-(4-isothiocyanatophenyl)-3-(pyridin-2-il)prop-2-en-1-one by treating 1,1-dimethyl-3-(4-(3-(pyridin-2-il)-acryloyl)-phenyl)thyourea with acetic anhydride. For all obtained compounds in the course of reaction the antileukemia activity was investigated</description>
</descriptions>
<formats>
<format>application/pdf</format>
</formats>
</resource>