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577.161.1:612.015.6 (1) |
Bazele materiale ale vieții. Biochimie. Biologie moleculară. Biofizică (657) |
Fiziologie. Fiziologie umană și comparată (719) |
SM ISO690:2012 CASTRAVEŢ, Ion. Studiu privind acţiunea vitaminei A asupra organismului uman. In: Arta Medica , 2016, nr. 2(59), pp. 41-45. ISSN 1810-1852. |
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Arta Medica | |||||
Numărul 2(59) / 2016 / ISSN 1810-1852 /ISSNe 1810-1879 | |||||
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CZU: 577.161.1:612.015.6 | |||||
Pag. 41-45 | |||||
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The naturally occurring compounds having vitamin A activity and the synthetic analogues of retinol, with or without vitamin A activity, are included in the term „retinoids”. Vitamin A and related compounds (retinoids) have been implicated in a number of useful and necessary biological functions. Retinoids are seen as an essential factor in the process of vision and as fundamental mediators of cell differentiation and cell proliferation. The potential effect of retinoids on the immune system has only increased the spectrum of its applications. The relevance of these findings suggests that they could play an important role in the clinical medicine as their relatives - the steroids. The problems encountered in determination of Vitamin A in pharmaceuticals are similar to those in food. Saponification followed by solvent extraction is the most usual technique employed to prepare samples for Vitamin A analysis. Direct extraction without saponification has been also used, but to a lesser extent. Generally, the former is used for total retinol determination, whereas direct extraction allows the separation and determination of retinol and the different retinyl esters. This paper describes also a simple and rapid procedure for determination of Vitamin A in pharmaceutical products and not only. |
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Cuvinte-cheie Vitamin A, identification, action, extraction, human body |
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