Background: Official statistics worldwide shows an unexpected bleak in terms of health of young people: cranio-cerebral trauma is the main cause of death in people aged under 40 years and also is responsible for approximately two-thirds of traumatic deaths, constituting the most commonly posttraumatic generator of permanently disabled. Thus, cranioplasty remains on the agenda and an interest is not only medical but also social. Materal and methods: Underlying work is accumulated material in the Division of Pediatric Neurosurgery Institute of Mother and Child. The control group consisted of 60 (100%) children who received the implants protacril cranioplasty – 30 (50%) children and allografts formalinizate - 30 (50%) children. The results of operations were estimated by the same clinical criteria and morpho, according to background lot of operated patients. The group was composed of 50 (100%) children who have benefited from cranioplasty plates of osteomatrix. Results: Comparative characteristic of methods and results of cranioplasty showed that cranioplasty combined with OMF-Plate and OMF-Paste is the least traumatic method of cranioplasty. Conclusions: Cranioplasty with osteoinductive biomaterials represents a more effective closure of cranial defect in patients who have suffered head trauma, this being proved by investigating neuroecography, cranial computed tomography and radiography. Due to the active regeneretive process there were no signs of cranioplasty in patioents 20 years after the operation. Objectively, it shows a good cosmetic effect. When examining the defects of skull limits are not visible.