Photometric determination of Fe (III) with sulfosalicylic acid using the standard addition method in oral drops Ferropol
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543.422.7:615.15 (1)
Metode de analiză spectrală. Metode de analiză optică (68)
Farmacia în general şi profesia de farmacist (184)
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OPREA, Vasile, VALICA, Vladimir, CHEPTĂNARU, Constantin, NISTORICA, Mihai, REMIŞ, Vladimir. Photometric determination of Fe (III) with sulfosalicylic acid using the standard addition method in oral drops Ferropol. In: Curierul Medical, 2016, nr. 2(59), pp. 11-14. ISSN 1875-0666.
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Curierul Medical
Numărul 2(59) / 2016 / ISSN 1875-0666

Photometric determination of Fe (III) with sulfosalicylic acid using the standard addition method in oral drops Ferropol
CZU: 543.422.7:615.15

Pag. 11-14

Oprea Vasile1, Valica Vladimir1, Cheptănaru Constantin1, Nistorica Mihai1, Remiş Vladimir2
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Academy of Sciences of Moldova
 
 
Disponibil în IBN: 27 mai 2016


Rezumat

Background: Iron deficiency in the human body decreases the hemoglobin level and so iron deficiency anemia occurs. In this case, doctors recommend the use of medical preparations in different forms: solid or liquid. Material and methods: In order to determine the quantity of Iron (III) in different medical preparations that contain Iron (III)-hydroxide polymaltose complex the analysis starts with the breakdown of the complex in acidic media. At the interaction of the mineral acids with Fe (III) hydroxide polymaltose complex during heating the brown color disappears and Fe (III) ions pass into the solution. results: It was shown that iron forms with sulfosalicylic acid a red-violet compound in acid media that absorbs light at a wavelength of 505 nanometers. The object of the study consists in the photometric method of the analysis of Fe in liquid forms, with the addition of sulfosalicylic acid using the standard addition method. Due to the fact that in a basic medium Fe (II) gently oxidizes to the Fe (III), then by the photometric method with sulfosalicylic acid it is quantitatively determined even Fe (III), as well as the summary content of Fe (II) and Fe (III) in the analyzed solution. conclusions: A new method of iron analysis was developed. It can be recommended to determine the iron in liquid medical preparations.

Cuvinte-cheie
iron deficiency, quality assurance,

photometric determination of iron, analysis of iron