A sequential dual cleavage of the arylsulfamate linker to provide both sulfamate and phenol derivatives
Închide
Conţinutul numărului revistei
Articolul precedent
Articolul urmator
387 3
Ultima descărcare din IBN:
2017-04-12 22:04
Căutarea după subiecte
similare conform CZU
547.466:542.95 (1)
Chimie organică (228)
Reacţii chimice. Procese chimice speciale (28)
SM ISO690:2012
FOURNIER, Diane; CIOBANU, Liviu; POIRIER, Donald. A sequential dual cleavage of the arylsulfamate linker to provide both sulfamate and phenol derivatives. In: Chemistry Journal of Moldova. 2015, nr. 2(10), pp. 68-76. ISSN 1857-1727.
10.19261/cjm.2015.10(2).09
EXPORT metadate:
Google Scholar
Crossref
CERIF

DataCite
Dublin Core
Chemistry Journal of Moldova
Numărul 2(10) / 2015 / ISSN 1857-1727 /ISSNe 2345-1688

A sequential dual cleavage of the arylsulfamate linker to provide both sulfamate and phenol derivatives

CZU: 547.466:542.95
DOI: 10.19261/cjm.2015.10(2).09
Pag. 68-76

Fournier Diane, Ciobanu Liviu, Poirier Donald
 
CHU de Quebec – Research Center (CHUL, T4)
 
Disponibil în IBN: 28 decembrie 2015


Rezumat

Tyramine sulfamate was linked to the trityl chloride resin and this polymeric solid support used to introduce two levels of molecular diversity by formation of peptide bonds. A dual cleavage strategy next generated in a sequential way (without resin split) two different types of compounds (phenol and arylsulfamate derivatives), which are therapeutically attractive types of compounds. Here, we used tyramine as a general scaffold, but other arylsulfamate derivatives could be judiciously used to extend the nature of synthesized compounds.

Cuvinte-cheie
solid-phase synthesis, linker, sulfamate,

phenol,

library