Cultivation of the vine was only possible by the peoples with an sedentary lifestyle. During the development of civilization the agricultural activities, including wine, have generated and conditioned the development of different complementary specific crafts. Production of derivatives wine (grapes, raisins, wine, distilled, juices etc.) make the knowledge of production technologies and their storage, which requires a certain level of knowledge, technology and culture. The knowledge obtained were transmitted from generation to generation and also supplemented with new achievements and technological principles, thus helping to improve product quality grape and prolonging the periods allowed validity. Nutritional and therapeutic value of derivatives wine is known and used in medical practice since ancient times. Hippocrates in Ancient Greece and Iranian doctor Razes (864-926) at length used grapes and grape juice in treatment of many diseases internal and external. Ampelotherapy in the XIXth century, based on results achieved in medicine, biology, biochemistry, is applied widely in France, Germany, Italy, Switzerland, Crimea etc.