Some aspects of biomedical preclinical research involving laboratory animals
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579.61:615.12.03:174 (1)
Microbiologie aplicată (110)
Farmacia în general şi profesia de farmacist (81)
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PARII, Sergiu; UNGUREANU, Alina; RUSNAC, Liliana; NICOLAI, Eugeniu; VALICA, Vladimir. Some aspects of biomedical preclinical research involving laboratory animals. In: Curierul Medical. 2015, nr. 4(58), pp. 55-57. ISSN 1875-0666.
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Curierul Medical
Numărul 4(58) / 2015 / ISSN 1875-0666

Some aspects of biomedical preclinical research involving laboratory animals

CZU: 579.61:615.12.03:174
Pag. 55-57

Parii Sergiu, Ungureanu Alina, Rusnac Liliana, Nicolai Eugeniu, Valica Vladimir
”Nicolae Testemițanu” State University of Medicine and Pharmacy
Disponibil în IBN: 27 iulie 2015


Background: Animal research has enormous utility as understanding the complex interactions of molecular mechanisms, biochemical and physiological study ultimately depends on intact organisms in vivo. The use of animals for biomedical research was the subject of much debate and continues to be today. The main question of this debate is whether or not correct, morally speaking, to conduct animal research. Scientists who use animals for these purposes mean that experiments should be done as humanely as possible. They agree that animals should not be used as long as there are testing methods producing similar results. Internationally these principles are reflected in the rules developed by the Organization for Economic Cooperation and Development for Good Laboratory Practice. However, the implementation of this legislation in our country aims at purchasing proper equipment of scientific laboratories for preclinical research, monitoring biomedical ethics and ensures quality results. The experimental ethics is a prerequisite for ensuring good scientific practice. Conclusion: The existence of a regulatory body to provide advice and evaluation of experimental design becomes mandatory enforcement of the concept of ethics in laboratory animal experiments.

animals, ethics,

preclinical research.