The study includes researches of several aspects of the immunologic impact, which hinders the maturation process of the nervous system of foetuses and newborns coming from mothers with a history of risk of abortion. We studied the phospholipids level and antiphospholipids in the blood cells of these pregnant women and their newborns. The phospholipids serve as plastic material, producing neuronal and cell membranes (phosphoglycerols), and myelin (swingophospholipids). Emergence of Ab-antiphospholipids at placental level, leads to alterations through antigenic similarity between the phospholipids from neuronal membranes and myelin, thus perturbing the development and maturation of the nervous system of foetus.

Studiul prevede cercetarea unor aspecte ale impactului immunologic, care are efect de frînare asupra maturatiei sistemului nervos la fetii si nou-nascutii de la mame cu iminenta de întrerupere a sarcinii în anamneza . Am studiat nivelului de fosfolipide si anticorpi antifosfolipidici în singele acestor gestante si nou-nascutilor proveniti de la ele. Fosfolipidele servesc drept material plastic, formînd membranele celulare (fosfoglicerolii), inclusiv si neuronale, si mielina (sfingofosfolipidele). Aparitia Ac-antifosfolipidici la nivel de placenta , duce la alterari prin asema nare antigenica a fosfolipidelor din membranele neuronale si mielna, astfel perturbînd dezvoltarea si maturatia sistemului nervos la fat.