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SM ISO690:2012 VLASOV, Lilia, MATCOVSCHI, Serghei, SASU, Boris, TCACIUC, Eugen. Estimarea activităţii agenţilor vasoconstrictori şi vasodilatatori renali la pacienţii cu ciroze hepatice
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2010, nr. 3(11), pp. 107-112. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 3(11) / 2010 / ISSN 1857-1719 | ||||||
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Pag. 107-112 | ||||||
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The estimation of renal vasoconstrictive and vasodilatative agents activity in patients with liver cihrrosis
The mechanisms leading to altered renal blood flow and renal function in patients with
liver cirrhosis are not entirely clear. Renal vasoconstriction is believed to be secondary to a
reduction in effective arterial volume in severe cirrhosis. Vasoconstrictive activation of
Endotelin- 1 , the role of Prostaglandin E -2 in regulation of renal blood flow were evaluated at
80 patients with liver cirrhosis, recruited into groups.The results show the vasoconstrictive
effect of Endotelin-1 with it significantly increased level and the inhibited levels of
Prostaglandin E 2 in decompensated cirrhosis produces negative effects on renal blood flow. |
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