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Articolul precedent |
Articolul urmator |
997 12 |
Ultima descărcare din IBN: 2022-02-03 21:11 |
SM ISO690:2012 FATHIBAROUD, AllaaM., CASIAN, Igor, DIUG, Eugen, GURANDA, Diana, DIUG, Octavian. Studiul disponibilităţii farmaceutice a spironolactonei din comprimate orodispersabile
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2010, nr. 1(11), pp. 456-459. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | |||||
Numărul 1(11) / 2010 / ISSN 1857-1719 | |||||
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Pag. 456-459 | |||||
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Study of the pharmaceutical availability of the spironolactone from orally disintegrating tablets
Was elaborated and studied 10 formulations orally disintegrating tablets with spironolactone,
to increase the pharmaceutical availability and was calculated the time of dissolution of 50% of substance. The solid dispersion with spironolactone, increase the substance solubility. Solid dispersion with PEG 4000 and PVP, content polysorbate 60 have the low time of dissolution 50%. |
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