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SM ISO690:2012 COVANTSEV, Serghei, CIOLAC, Dumitru. The role of mast cells in inflammatory reaction in burn injury and postburn regeneration. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2013, nr. 1(14), pp. 64-70. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | |||||
Numărul 1(14) / 2013 / ISSN 1857-1719 | |||||
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Pag. 64-70 | |||||
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Rezumat | |||||
Each year, approximately 11 million patients are hospitalized due to burn injuries. Mortality from burns ranges from 1.4% to 18% (Europe). At the same time burn injuries can lead to disability, and full recovery is often impossible. Mast cells can play an important role in burn injuries and regeneration. For a long time these cells had been neglected by scientists. Only recently new data has started to appear about their structure and functional significance in the local homeostasis. The list of substances synthesized by mast cells has significantly expanded, and so has the list of cells which they can influence. A review of studies on mast cells regarding their role in burn injury and its subsequent regeneration is presented in this article. |
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