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Ultima descărcare din IBN: 2019-04-11 07:54 |
SM ISO690:2012 BOTEA, Olga, IACOB, Sergiu, AMBROS, Ala, LÎSÎI, Leonid. Rolul contraversat al H2s în stările critice. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2010, nr. 1(11), pp. 300-309. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | |||||
Numărul 1(11) / 2010 / ISSN 1857-1719 | |||||
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Pag. 300-309 | |||||
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The role contraversale of h2s in critical condition
Since the discovery of endogenously-produced hydrogen sulfide (H2S) in various tissues,
there has been an explosion of interest in H2S as a biological mediator alongside other gaseous mediators such as, nitric oxide and carbon monoxide. The identification of enzyme regulated H2S synthetic pathways in the cardiovascular system has led to a number of studies examining specific regulatory actions of H2S. Several molecular mechanisms of action of H2S have been described. These include interactions of H2S with NO, redox regulation of multiple signaling proteins and regulation of KATP channel opening. H2S holds promise as an endogenous mediator controlling a wide range of cardiovascular cell functions and integrated responses under both physiological and pathological conditions and may be amenable to therapeutic manipulation. |
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