Rat spleen lysosomal enzymes activities changes in aseptic inflammation and under the influence of sulphated polysaccharides The aim of the study was to evaluate the influence of sulphated polysaccharides from the cyanobacteria Spirulina platensis (PSS) biomass upon the activity of lysosomal enzymes in aseptic inflammation. PSS had positive influence on different magnitude in aseptic inflammation, which was demonstrated by the increase of the activities of acidic phosphatase, Nacetyl- β-glucosidase, β-glucosidase, arilsulfatase C and the dicrease of cathepsin D activity. PSS can be considered a pathogenic remedy for the correction of the metabolic disturbances in the spleen induced by aseptic inflammation.

Studiul efectuat a fost axat pe cercetarea influenţei polizaharidelor sulfatate extrase din biomasa cianobacteriei Spirulina platensis (PSS) la administrarea enterală asupra activităţii enzimelor lizozomale în splină în inflamaţia aseptică. Rezultatele studiului denotă efecte pozitive de magnitudine diferită ale administrării PSS în inflamaţia aseptică, ce se manifestă prin creşterea activităţii fosfatazei acide, N-acetil-β-glucozidazei, β-glucozidazei, arilsulfatazei C şi reducerea activităţii catepsinei D. PSS pot fi considerate remediu patogenic de corecţie a dereglărilor metabolice în splină provocate de inflamaţia aseptică.