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SM ISO690:2012 BUTOROV, Ivan, CHIKH, AhmadMahmoud, BUTOROV, Valentina, COŞCIUC, Irina, ANTONOVA, Natalia. Modificarea markerilor inflamaţiei la bolnavii cu bronhopneumopatie cronică obstructivă
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2009, nr. 3(10), pp. 192-196. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 3(10) / 2009 / ISSN 1857-1719 | ||||||
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Pag. 192-196 | ||||||
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The inflammatory markers modification in patients with chronic obstructive pulmonary disease
The comparative efficiency of long term use of fenspirid and atrovent in 42 patients with
chronic obstructive pulmonary disease was studied. It was noted that the 6 months administration of fenspirid contributed to a 2,6 times cough intensity decrease and atrovent – a 1,2 time decrease. The anti-inflammatory therapy had a positive effect on the level of proinflammatory cytokines that registered a 3 times decrease in patients that used fenspirid and 1,5 time decrease after atrovent. During the long term treatment with fenspirid VEF1 increased by 35,5% and by 21,2% - during the basic therapy. |
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