It was showed up the concept of the informational system support within the process of projects expertise in the areas of science, innovations and technological transfer, which is elaborated by the Expertise Consultative Council in collaboration with the Resource and Informational Networks Center of Moldova Academy of Sciences, according to the Decision of the Supreme Council for Science and Technological Development. The Informational System is projected as a family of informational working stations, built on relational data base technology and modern communication technologies. There were stated the technological methods oriented on applications obtaining with following qualities: elaboration productivity, systems adaptability to application domain evolution, maintenance and development by final user without the assistance of developer, liability and security, economy of elaboration resources.