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SM ISO690:2012 TODIRAŞ, Nadejda, COREŢCHI, Ianoş. Analiza comparativă a acţiunii derivaţilor izotioureici profetur şi metiferon în reactivitatea vasculară adrenergică
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2009, nr. 1(10), pp. 300-303. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(10) / 2009 / ISSN 1857-1719 | ||||||
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Pag. 300-303 | ||||||
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A comparative analysis of the effects of isothiourea derivates profetur
and metiferon on the adrenergic vascular reactivity The purpose of this study was to investigate the effects of S-isothiourea derivates metiferon and profetur on the noradrenalin and phenylephrine induced vasoconstriction. Using organ bath
technique, were examined contractility of isolated thoracic aorta rings from the rat. We establish that pretreatment with metiferon and profetur significantly increased vasopressor effects of neselective adrenergic receptor agonist noradrenaline and α1 selective receptor agonist phenylephrine. Further investigation is required to ensure the effects of new S-isothiourea derivates on systemic arterial pressure hypotension. |
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