Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
956 16 |
Ultima descărcare din IBN: 2021-10-01 15:25 |
SM ISO690:2012 UNGUREANU, Margareta, TUCHILUS, Cristina. Studiu privind sinteza şi acţiunea antibacteriana si antimicotica a unor noi derivaţi ai sulfamidelor. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2010, nr. 1(11), pp. 349-353. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(11) / 2010 / ISSN 1857-1719 | ||||||
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Pag. 349-353 | ||||||
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We decided to obtain new bioactive substances by inserting the radicals of thyoureea to the N4 atom of Davosine, a sulphamide with important therapeutic properties. We have treated this sulphamide with various aromatics isothyocianates, obtaining eight new derivatives of thyoureea The chemical structure of the new compounds was confirmed by C,H,N elemental and spectral analysis. We have tested the antibacterial and antifungal activity of the new synthesised products through the diffusimetric method. The assay was made on Gram-positive and Gram-negative bacteria and on some species of Candida.We have elaborated a simple method for obtaining new sulphamides derivatives. This study represent a premiss for obtaining new antibacterial and antifungal derivatives of sulphamides. |
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