The aim of the research was to study the health status of women of reproductive age engaged in dangerous and hazardous occupations. Materials and methods used: 204 workers with 20 years and more of experience from a sewing factory in Bakihanova. The 1st group comprised 88 ironing specialists, 2nd - 88 sewers and cloth laying up/cutting specialists, 3rd - 28 workers (economists and HR specialists). Laboratory studies included a detailed analysis of peripheral blood in which estimated the level of hemoglobin, erythrocyte, reticulocyte, number of leukocytes and other results of the study. The number of persons with leukocytes in the 2nd group was of 6,9; in the 3rd group - 3,9, while leucopenia was discovered in all groups. Lymphocytes - 34,9 in the 1st and 2nd groups. Segmented neutrophyles were within normal limits - 60,5. Shared neutrophyles - 9,4 in the fi rst group, 11,3, in the 2nd group, and 4,4 in the third group. A change in the Kalfa- Kalifa index was discovered, that reached its maximum value in people with 10-19 years of work experience (44,1). Red blood in the fi rst group - 12,4; 2nd group - 4,6; third group - 4,26, while the average fi gures for all 3 groups is 4,15. Hemoglobin indicator in the 3rd group - 80,7; in the second group - 96,2. Given the above said we came to the fi ndings that decreasing the duration of work in this factory has impact on the peripheral blood.