Research survey on iridoid and phenylethanoid glycosides among seven populations of Euphrasia rostkoviana Hayne from the Alps
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MARI, Angela, CIOCARLAN, Alexandru, AIELLO, Nicola, SCARTEZZINI, Fabrizio, PIZZA, Cosimo, AMBROSIO, Michele. Research survey on iridoid and phenylethanoid glycosides among seven populations of Euphrasia rostkoviana Hayne from the Alps. In: Phytochemistry, 2017, nr. 137, pp. 72-80. ISSN 0031-9422. DOI: https://doi.org/10.1016/j.phytochem.2017.02.013
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Phytochemistry
Numărul 137 / 2017 / ISSN 0031-9422 /ISSNe 1873-3700

Research survey on iridoid and phenylethanoid glycosides among seven populations of Euphrasia rostkoviana Hayne from the Alps

DOI:https://doi.org/10.1016/j.phytochem.2017.02.013

Pag. 72-80

Mari Angela1, Ciocarlan Alexandru2, Aiello Nicola3, Scartezzini Fabrizio3, Pizza Cosimo1, Ambrosio Michele2
 
1 University of Salerno,
2 Universitatea din Trento,
3 Forest Monitoring and Management Research Unit, Trento
 
 
Disponibil în IBN: 13 februarie 2023


Rezumat

The traditional use of extracts of Euphrasia rostkoviana to relieve ocular inflammation or infections is well documented and supported by clinical studies. Various classes of chemical compounds such as iridoids, phenylethanoids, flavonoids and hydroxycinnamic acids have been reported. The present work aims to assess the chemical diversity among seven populations of Euphrasia rostkoviana found in northern Italy. A meticulous separation of components led to the isolation and structural characterization of two previously unrecorded phenylethanoids methoxycrassifolioside and deoxycrassifolioside and one previously undescribed terpene glucoside (1E,6E)-8-hydroxy-3,7-dimethyl-octa-1,6-dienyl 1-O-β-D-glucopyranoside. We have also identified known phenylethanoids and iridoids that are reported in this genus for the first time. Finally, a targeted quantitative analysis for the standardization of herbal preparations revealed that iridoids occur in all populations whereas the presence and the levels of rutin and phenylethanoids are highly variable.

Cuvinte-cheie
Citronellenyl glucoside, Crassifolioside, Ehrenoside, Euphrasia rostkoviana, iridoids, Orobanchaceae, phenylethanoid glycosides, verbascoside