Evaluarea eficacităţii şi siguranţei atomoxetinei la copiii cu tulburare hiperactivitate/deficit de atenţie
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DIACONU, Georgeta, GRIGORE, Ioana, IORDACHE, C., TRANDAFIR, Laura. Evaluarea eficacităţii şi siguranţei atomoxetinei la copiii cu tulburare hiperactivitate/deficit de atenţie. In: Buletin de Perinatologie, 2009, nr. 3(43), pp. 202-205. ISSN 1810-5289.
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Buletin de Perinatologie
Numărul 3(43) / 2009 / ISSN 1810-5289

Evaluarea eficacităţii şi siguranţei atomoxetinei la copiii cu tulburare hiperactivitate/deficit de atenţie

Pag. 202-205

Diaconu Georgeta, Grigore Ioana, Iordache C., Trandafir Laura
 
 
 
Disponibil în IBN: 16 decembrie 2013


Rezumat

Attention-defi cit/hyperactivity disorder (ADHD) is associated with impairments in educational, occupational, neuropsychological and family and social functioning in children. Atomoxetine (ATMX) is the fi rst nonstimulant drug approved for the treatment of ADHD in 6 years of age children and adolescents. The aim of this study is to evaluated ATMX efficacy and safety in 43 children with ADHD. The dose was gradually increased from 0,5 mg/kg/day to a maximum of 1,8 mg/kg/day based on efficacy and tolerability assessed by the investigator. After 6 month 72,09% of children showed response of treatment with ATMX, with significant reductions in ADHD Rating Scale-IV-Parent Version: Investigator- Administered and Scored and Clinical Global Impression ADHD Severity Scale scores. No serious adverse event were observed. Treatment with ATMX is efficacy and safety in children with ADHD and represent a nonstimulant therapeutic alternative.

Cuvinte-cheie
attention-defi cit/hyperactivity disorder, atomoxetine,

child