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616.36-089.843-036:614.2 (1) |
Patologia sistemului digestiv. Tulburări ale tubului alimentar (1732) |
Organizarea publică şi profesională a sănătăţii (871) |
SM ISO690:2012 PÎRVU, Victor, TARAN, Natalia, HOTINEANU, Adrian. Risk factors for 90-day mortality in patients on the liver transplant waiting list. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 330. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.36-089.843-036:614.2 | ||||||
Pag. 330-330 | ||||||
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Background. Management of patients on the liver transplant waiting list is of paramount importance in improving post-transplant survival. Objective of the study. Assessment of risk factors for 90 days mortality from the waiting list of the liver transplant program from in the Republic of Moldova. Material and Methods. The retrospective (20132018) and the prospective (2018-2022) included 265 patients listed for liver transplantation (154 men (58.11%) and 111 women (41.88%)). Using binary logistic regression analysis, we analyzed risk factors for 90-day mortality in patients on the liver transplant waiting list. Results. From the 265 patients on the waiting list (age 47.75 ± 9.99 years) - 37 (13.96%) died within the first 90 days of listing. Risk factors for 90 days mortality after listing were: creatinine level (Odds Ratio (OR) = 1.027; 95% CI = 1.016-1.038; p < 0.001); bilirubin (OR = 1.015; 95% CI = 1.009-1.021; p < 0.001); viral etiology (hepatic type Delta virus - HDV) (OR = 0.080; 95% CI = 0.14-0.457; p = 0.004) and the presence of hepatocellular carcinoma (HCC) (OR = 0.173; 95% CI = 0.046-0.655; p = 0.01). The peculiarity of the liver transplant program is the influence of HDV on the mortality of patients from the waiting list. Conclusion. 90-day mortality in patients on the waiting list for the liver transplant program in the Republic of Moldova was significantly influenced by creatinine, bilirubin, HDV and HCC. |
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Cuvinte-cheie risk factors for 90 days mortality, waiting list, liver transplant, factori de risc pentru mortalitatea la 90 de zile, lista de aşteptare, transplant hepatic |
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