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Ultima descărcare din IBN: 2024-04-01 13:22 |
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616.24-002.5-036-053.2]:616.98:578.828HIV (1) |
Patologia sistemului respirator. Tulburări ale organelor de respiraţie (757) |
SM ISO690:2012 KULCITKAIA, Stela, IVANES, Igor, ABU MILAD, Odai Mousa. The evolution of tuberculosis in children living with human immunodeficiency virus infection . In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 229. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.24-002.5-036-053.2]:616.98:578.828HIV | ||||||
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Background. Tuberculosis (TB) is one of the top ten causes of death in children around the world. HIV infection in children is a major risk for tuberculosis-disease and the reactivation of latent infection with Mycobacterium tuberculosis. The WHO estimates that approximately 2.5 million children were living with HIV infection in 2019. Objective of the study. Studying of the peculiarities of the evolution of TB in children living with HIV infection. Material and Methods. Analysis of 33 cases of children with TB/HIV coinfection, diagnosed between 2009-2020, hospitalized for treatment in the Municipal Clinical Hospital of Phthisiopneumology, Chisinau, were included in the study. Results. Age of children: 6-18 years – 17 (51.5%), 0-3 years – 9 (27.3%), 4-6 years – 7 (21.2%) children. Detected by address – 26 (78.8%) and 7 (21.2%) children as contact. Unvaccinated BCG – 23 (69.7%) children. Associated children’s diseases: peripheral lymphadenopathy – 14 (42.4%) cases, anemia – 13 (39.4%), bronchopulmonary infections – 12 (36.4%) cases. „New case” of TB were 27 (81.8%), „Recurrence” – 4 (12.1%) and „Therapeutic failure” – 2 (6.1%) children. Extrapulmonary TB was established in 20 (60.5%) and pulmonary TB – 13 (39.5%) cases. Microbiological confirmation by culture – 18 (55%) cases. Tuberculosis developed in children with HIV status in 17 (51.5%) children. Treatment for sensitive TB was administered in 26 (78.8%), resistant tuberculosis – 7 (21.2%) cases. Therapeutic results: „cured” or „completed treatment” – 28 (84.85%), therapeutic failure – 5 (15.15%) cases. Conclusion. Children with HIV have an increased risk of developing TB, especially in cases without ARV therapy. The development of TB/HIV coinfection is determined by social and epidemiological factors. |
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Cuvinte-cheie tuberculosis, HIV infection, children, tuberculoza, infecție HIV, copii |
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