| Articolul precedent |
| Articolul urmator |
 |
 281 27 |
| Ultima descărcare din IBN: 2023-10-23 17:44 |
| Căutarea după subiecte similare conform CZU |
| 547.497 (31) |
| Chimie organică (484) |
 SM ISO690:2012CIURSIN, Andrei, RUSNAC, Roman, GULYA, Aurelian. Synthesis of n-cyclohexyl-2-[(3-ethoxy-2- hydroxyphenyl) methylidene] hydrazine-1- carbothioamide. In: Life sciences in the dialogue of generations: connections between universities, academia and business community, Ed. 2, 29-30 septembrie 2022, Chişinău. Chișinău, Republica Moldova: Moldova State University, 2022, p. 210. ISBN 978-9975-159-80-7. |
| EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
| Life sciences in the dialogue of generations: connections between universities, academia and business community 2022 | ||||||
|
Conferința "Life sciences in the dialogue of generations: connections between universities, academia and business community" 2, Chişinău, Moldova, 29-30 septembrie 2022 | ||||||
|
||||||
| CZU: 547.497 | ||||||
| Pag. 210-210 | ||||||
|
||||||
 Descarcă PDF |
||||||
| Rezumat | ||||||
The recently studied thiosemicarbazones have exceeded researchers' expectations by demonstrating advanced pharmacological effects, such as anticancer, antibacterial and antioxidant effects. The paper presents the synthesis of new ligand N-cyclohexyl-2-[(3-ethoxy-2- hydroxyphenyl) methylidene] hydrazine-1-carbothioamide (H2L) obtained through the addition of 2-ethoxy-6-[hydrazinylidenemethyl] phenol to isothiocyanatocyclohexane. Figure. Synthesis of N-cyclohexyl-2-[(3-ethoxy-2-hydroxyphenyl) methylidene] hydrazine-1-carbothioamide (H2L) i- CSCl2, CaCO3, H2O, (extracts with CH2Cl2), 2 h; ii- 2-ethoxy-6-[hydrazinylidenemethyl]phenol (preferred name - hydrazone to 3-ethoxyalicylaldehyde) tetrahydrofuran, 1.5 h. Thiosemicarbazone H2L was characterized on the basis of various spectroscopic techniques like FTIR, 1H and 13C NMR studies, elemental analysis. The compound was subjected to antimicrobial and antifungal activity screening using serial broth dilution method. The thiosemicarbazone H2L showed moderate activity against: Staphylococcus aureus, Bacillus cereus, Escherichia coli, Acinetobacter baumannii and Candida albicans. |
||||||
| Cuvinte-cheie antifungal, Antimicrobial, dilution method, pharmacological effects, thiosemicarbazone H2L. |
||||||
|
|
|
|
