Zoonoses are contagious diseases caused by various pathogens (prions, viruses, bacteria, fungi, protozoa, helminths, arachnids, insects), common to humans and animals, and represent a major public health problem. Pygmy field mouse inhabits the forest edge and open-type biotopes: meadows, grasslands, agrocoenoses, fallow ground. It is a species with a lower frequency compared to other small rodents and has accessorial ecological significance. The aim of the study was to describe the epidemiological characteristic of the parasite fauna in Apodemus uralensis (Pallas, 1771). The research was conducted in the laboratory of Parasitology and Helminthology of the Institute of Zoology, on A. uralensis captured from various biotopes of the Republic of Moldova. Laboratory parasitological investigations were performed by total dissection of previously euthanized rodents, with microscopic examination of the muscles (masseter muscles, arms, diaphragm) and internal organs (trachea, lungs, heart, tongue, esophagus, stomach, small intestine, large intestine, liver, spleen, kidney, bladder) in order to establish the structure of the helminthofauna and to determine the parasitological indices. The identification of the species was performedaccording to morphological criterion according to standard methods. The taxonomic structure of the identified parasitic species falls into 3 classes, 7 orders, 13 families, 14 genera and 15 species. There are 3 species (Syphacia stroma, Syphacia obvelata, Strongyloides ratti) in the category of parasitoses with zoonotic impact (parasitozoonoses), in the one with mixed impact (zoonotic + epizootic) there are 3 species (Hydatigera taeniaformis larvae, Capillaria hepatica), and in the category of rodent invasions there are 7 species (Paranoplocephala omphaloides, Catenotaenia cricetorum, Skrjabinotaenia lobata, Rodentolipis straminea, Heligmosomoides polygirus, Mastophorus muris, Trichuris muris). The nosological characteristics of helminthoses includes 2 categories: Cestodoses teniosis - 10.0%, mesocestoidosis, paranoplocephalosis - 10.0%, catenoteniosis - 5.0%, cryabinoteniosis - 10.0%, hydatigeriosis - 10.0%); Nematodes (syphacioosis - 20.0%, strongyloidosis - 15.0%, capillaries -15.0%, heligmosomiasis - 5.0%, trichurosis - 15.0%, rodentolepiosis-5.0, mastophoresis - 20.0%). The epidemiological feature includes 3 categories of parasitic species. The small rodents parasitofauna monitoring in different areas has a biomedical and epidemiological importance, in order to prevent the transmission of invasive forms to humans and other mammals involved in the biological cycles of parasites with zoonotic and epizootic role. Therefore, there are necessary measures to decrease the level of infestation in wild animals.