Antimycobacterialagentson the pharmaceutical market of Moldova
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UNCU, Andrei, VALICA, Vladimir, DONICI, Elena, MOISEEV, Ana, SUVORCHINA, Olga. Antimycobacterialagentson the pharmaceutical market of Moldova. In: Archives of the Balkan Medical Union Supliment, 2013, nr. S3(48), p. 105. ISSN 0041-6940.
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Archives of the Balkan Medical Union Supliment
Numărul S3(48) / 2013 / ISSN 0041-6940

Antimycobacterialagentson the pharmaceutical market of Moldova


Pag. 105-105

Uncu Andrei, Valica Vladimir, Donici Elena, Moiseev Ana, Suvorchina Olga
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 2 noiembrie 2022


Rezumat

Treatmentof various forms oftuberculosisis complex, using medicines ofdifferent pharmacotherapeuticgroups. But avery important is theethiotropictreatmentwithantiTB drugs, divided in some groups:Hydrazides, antibiotics, p-aminosalicylicacid derivatives, tiocarbamides,butanolderivates. Purpose: evaluation of the arsenal of drugs used to treat tuberculosis in Moldova. Material and Methods: analysis of the State List of RM drugs as well, recommendations of the WHO and specialists in the field; statistical data processing. Results: According to the international classification ATC, the Collaborating Centrefor Statistical Methodology WHO recordedon 02/25/2013, in the J04Agroup, 17single international common name sand 6TB drug combinations. On the RMpharmaceuticalmarketcurrently 29 names of tuberculos is remediesare found, including eightinternationalcommon names, that means 47% ofthose recordedby WHO.Hydrazidesgroupcontaining 50% of all those recommendedby WHO, antibiotics -33.3%, salicylates -67%; the thiocarbamides group is not registering any records, other remedies- 50%. Combine dantituberculosisdrugsareabout 17%. Only onedrug ismade in RM (Isoniazid comp. 300 and 100mg and sol. Injection100mg/ ml), the rest being imported. Conclusions: Taking in consideration the rapid development of resistance to Mycobacterium tuberculosis, development of new drugs of this group and their implementation in the current production in RM is very actual in order to make sure that the population has a full access at a big variety of antimycobacterial medicines.

Cuvinte-cheie
antimycobacterialagents, pharmaceutical market, Moldova