In the Republic of Moldova, European beech Fagus sylvatica L. grows on the eastern border of its range, so even small climate changes can significantly affect the number of beech forests. Since the late 80s of the last century, an increase in the amount of direct and global solar radiation has been noted, accompanied by a decrease in the number of days without sun. The air temperature in the Republic of Moldova regularly breaks records and the average of annu-al temperature exceeds by at least 1.0-1.5°C (http://old.meteo.md/newru/last_season.htm). The absence of significant precipitation in early spring contributes to the drying of the upper layers of the soil, which creates not quite favorable conditions for the germination of beech seeds in natural conditions. The summer months are characterized by even more extreme conditions – the number of days with a maximum air temperature of ≥30ºС significantly increases with a signifi-cant deficit of precipitation. Taking into account the climate change, it seems relevant to identify some measures to improve the adaptive capacity of beech, especially from local populations. Purpose. The purpose of our work was to study the effect of the bioregulators such as genistifolioside and capsicoside on the germination of beech seeds originated from Cioresti, the Republic of Moldova, as well as on the adaptation and survival of seedlings in solarium conditions.