Neurastenic syndrome in algic form of chronic pancreatitis associated with gastrointestinal comorbidities
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UCRAINȚEVA, Violeta, ŢÎBÎRNĂ, Ion, EȘANU, Loretta, CAZACU, Veronica, CONAREVA, Lilia. Neurastenic syndrome in algic form of chronic pancreatitis associated with gastrointestinal comorbidities. In: Journal of Gastrointestinal and Liver Diseases, 2019, nr. S2(28), p. 55. ISSN 1841-8724.
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Journal of Gastrointestinal and Liver Diseases
Numărul S2(28) / 2019 / ISSN 1841-8724 /ISSNe 1842-1121

Neurastenic syndrome in algic form of chronic pancreatitis associated with gastrointestinal comorbidities


Pag. 55-55

Ucraințeva Violeta1, Ţîbîrnă Ion1, Eșanu Loretta2, Cazacu Veronica2, Conareva Lilia2
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 St. Archangel Michael Clinical Municipal Hospital
 
Disponibil în IBN: 24 august 2022


Rezumat

Objectives. There is an increase of the incidence of chronic pancreatitis (CP) in the recent population. This is due not only to the improvement of diagnostic methods, but also to the influence of increased alcohol consumption, increased exposure to environmental factors, affecting different protection mechanisms and other multiple risk factors (smoking, stress, etc.), as well as gastrointestinal comorbidities. Contemporary methods of instrumental and laboratory diagnosis allow the elaboration of a differential diagnosis between chronic diseases of the pancreas, stomach, duodenum, liver and gallbladder disorders. Regarding the knowledge of psychological characteristics in PC patients, less attention was paid, so it is important to apply the questionnaire for studying psychosomatic changes in CP patients with algic form to evaluate neurasthenic syndrome. The purpose of the study. To study the presence of gastrointestinal comorbidities in algic form of CP, and signs of anxiety and depression in patients with algic form of CP and neurastenic syndrome. Materials and methods. The study group consisted of 52 patients with CP, 22 patients with algic form of CP with clinically confirmed neurasthenic syndrome and Spilberg questionnaire (assessment of anxiety) and Beck (evaluation of depression), the patients were hospitalized in the Municipal Clinical Hospital „Sf. Arh. Mihail „, Chisinau, in 2018. For the determination of gastrointestinal comorbidities were performed fibrogastroduodenoscopy, colonoscopy and abdominal ultrasonography. Results. Out of 22 patients with algic form of CP the presence of depressive reactions was detected in 81.8%, in 18.2% of patients the depressive symptoms were absent. All depressive reactions were from mild to moderate: 72.2% mild depressive reactions and 9.6% - moderate depressive reactions. Depressive reactions were preponderent with anxiety and were accompanied by somatic equivalents. Duodenogastroesophageal reflux with bile was found in 63.6% of patients with neurasthenic syndrome, in 22.7% was erythematous-exudative gastritis and in 13.6% was gastric mucosal congestion. It is worth noting that in patients with duodenogastroesophageal reflux erosive bulbitis (35.7%) was found in patients more often then with erosive gastritis (21.4%). Biliary dyskinesia was found in 36.3% of patients and in 27.2% of patients was found the irritable bowel syndrome. Conclusions. 1. The high incidence of depressive reactions in algic form of CP has anxious and somatic aspects. Psychosomatic tools may be informative for confirming neurasthenic syndrome. 2. Gastrointestinal comorbidities in algic form of CP, with neurastenic syndrome are present in different range. It is important to use paraclinical methods in CP with neurasthenic syndrome for the detection of other organ disorders and for complex treatment.

Cuvinte-cheie
neurasthenic, pancreatitis, comorbidity