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SM ISO690:2012 COROBCEANU-NICOLAESCU, Nadejda, GHIDIRIM, Nicolae, COŞCIUG, Gurii, ANTOCI, Lilian, CODREAN, Lilia, GODOROJA, Vitalie, CATRINICI, Victor, DONSCAIA, Anna, MEDNICOV, Lorena, SUHARSCHI, Ilie, BURUIANĂ, Nicolae, CEBAN, V.. Dinamica indicilor exopancreatici în raport cu volumul operaţiilor radicale pe motiv de cancer gastric şi tratamentul conservativ aplicat. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2011, nr. 4(12), pp. 161-166. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | |
Numărul 4(12) / 2011 / ISSN 1857-1719 | |
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Pag. 161-166 | |
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Rezumat | |
Dynamics of exopancreatic indexes regarding the volume of radical
operation in case of gastric cancer and the conservativ treatment
In our study we have included 11 patients with gastric cancer radicaly operated, who
manifested an acute pancreatitis in the postoperative period. The patients have been examined in
the aspect of changing the enzimatic indexes: α-amilase, lipase, C-reactive protein and pancreatic
amilase (P-amilase). The first group consisted of 4 patients with direct and large injury of
pancreas within the radical enlarged and combined operations, were treated with contrical and
sandostatin. The second group was formed of 7 patients, who ungergone radical enlarged
operations, were treated only with contrical, so being motivated the easier evolution of acute
postoperative pancreatitis, due to a minimal injury of pancreas.
The radical enlarged and combined operations in gastric cancer increase the period of
hyperfermentemia and increase the risk of severe evolution of acute postoperative pancreatitis.
Values of plasmatic amilase to grow up beginning from the operation day and during the first
two days after operation, but the period of hyper-α-amilazemia is longer in case of radical
enlarged and combined operations. Values of lipase grow too during the first days after
operations, despite the data from literature, but the period of hiperlipazemia is longer in cases of
radical enlarged and combined operations. C-reactive protein increases during the first
postoperative days and maintains until the moment when patients go home. In cases of radical
enlarged operations with minimal injury of pancreas, contrical is recommended to be
administered intraoperatively and during the first postoperative days it is enough for reglation of
exopancreatic disorders. In cases of radical enlarged and combined operation with large direct
injury of pancreas or parapancreatic tissue, the administration of sandostatine in the first days
after operations is recommended. |
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