The study is an attempt to analyze the methods of cooperation of state bodies, empowered in ensuring the national security of the Republic of Moldova.Thesecurityparadigm is changing. The diversification of nature, scope, spectrum of conflicts, actors involved,as well as globalization, migration, geopolitical changes, developments in nature and balance of power, access of technological individuals to social resource management have generated new vulnerabilities and challenges in the categoryof threats to statesecurity.The power and diversity of hybrid threats and wars will continue to grow, posing a security challenge for governments. National governments fightfor economic influenceand control over critical economic infrastructures, monopolization of mass communication infrastructure, cyber-attacks, manipulation of public opinion through media sources, modeling of thinking through social media, etc.The Republic of Moldova is the only country in the region without a revised National Security Strategy, which endangers the security of the state and the population in the face of the emergence of both symmetric and asymmetric risks and threats.In this context, thecentral bodies of the state need much more intensive cooperation in the field of ensuring national security.