In recent years distributed information processing and high-performance computing technologies (HPC, distributed Cloud and Grid computing infrastructures) for solving complex tasks with high demands of computing resources are actively developing. In Moldova the works on creation of high-performance and distributed computing infrastructures were started relatively recently due to participation in implementation of a number of international projects. Research teams from Moldova participated in a series of regional and pan-European projects that allowed them to begin forming the national heterogeneous computing infrastructure, get access to regional and European computing resources, and expand the range and areas of solving tasks.