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Ultima descărcare din IBN: 2022-09-02 13:03 |
SM ISO690:2012 VETRILĂ, Snejana, MAZUR, Minodora, MANCUŞ, Stela. Dislipidemiile în cadrul polimiozitei şi dermatomiozitei. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2011, nr. 3(12), pp. 134-141. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 3(12) / 2011 / ISSN 1857-1719 | ||||||
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Pag. 134-141 | ||||||
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Dyslipidemia in polimyosotis and dermatomyositis
The idiopathic inflammatory myopathies (IIM) have reported lipid metabolism disorders. It
was demonstrated that the dose below 10 mg did not influence lipid spectrum. The aim: To
describe MII associated with deviations of lipid profile. Material and methods: The study group
included 20 patients with myopathies examined by validated instruments in rheumatology: 11 -
with polymyositis (PM) and 9 patients with dermatomyositis (DM), divided into two subgroups:
group I - 12 pts with dyslipidemia and group II – 8 pts with normal lipid profile indices. Results:
In study group women: men ratio was 1,8:1, the average age at onset - 43.0 ± 2.4 years, mainly
with PM. Dyslipidemia was installed more frequently in women of reproductive age in half cases
associated with dysmenorrea. Glucocorticosteroids (GCS) cumulative dose was more 15 g in
58.3% and 62.5% patients in group I and II which is considered high dose. The results of
Diseases Activity Score (DAS) were 9.55 vs 7.47 points in group I and II, respectively. Systemic
implications showed predominance of cardiovascular damage and nervous system in pts with
dyslipidemia. Conclusions: In IIM dyslipidemia is often installed in women, the average age and
correlates with high disease activity. Cumulative GCS dose and body mass index does not affect
lipid panels. |
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