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SM ISO690:2012 BUMACOV, Ludmila. Preparate care influenţează plasticitatea neuronală. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2011, nr. 1(12), pp. 347-351. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(12) / 2011 / ISSN 1857-1719 | ||||||
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Pag. 347-351 | ||||||
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Influence of different classes of drugs on neural plasticity
Recent studies demonstrate that neurogenesis, the creation of new brain cells, occurs in
the adult human. Many of these new neurons survive and integrate themselves into the working
brain, suggesting the potential for a self-healing brain.
Adult neurogenesis is an extremely dynamic process that is regulated in both a positive
and negative manner by environmental, endocrine, and pharmacological stimuli. This indicates
that neurogenesis is a form of neural plasticity that contributes to the ability of the brain to
process, adapt, and respond to stimuli.
Antidepressants (SSRI and tricycles) opiates, benzodiazepines, psychostimulants, and
other classes of drugs (antipsychotics, antiepileptics, analgesics) are known to have long-term
effects that are mediated by alteration of synaptic plasticity. In addition to their properties,
repeated use of these drugs can influence cognition, learning, and memory.
The focus of this work is to briefly describe influence of different drugs on neural
plasticity. |
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