Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
1201 15 |
Ultima descărcare din IBN: 2023-03-28 09:18 |
SM ISO690:2012 ŞAPTEFRAŢI, Lilian, MAZURU, Vitalie, DAVID, Valeriu, GLOBA, Tatiana, RUDICO, Lucian. Densitatea vasculară şi distribuţia vaselor sanguine în neoplazia cervixului uterin (dubla imunocolorare anti CD31/ anti-actina muşchiului neted-alpha). In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2011, nr. 1(12), pp. 104-110. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(12) / 2011 / ISSN 1857-1719 | ||||||
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Pag. 104-110 | ||||||
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Divergent expression of endoglin and marker of proliferation Ki67 in the
benign and malign lesions of the uterine cervix
In this study we show, for the first time, application of double immunohistochemical stain
method using endothelial marker of high specificity (CD105) and marker of proliferation (Ki67),
applied on the formalin fixed and paraffin embedded neoplazic specimens of the uterine cervix.
This method represents high accuracy in functional status interpretation of the blood vessels.
Based on obtained results, we want to propose a hypothesis according which the activation and
proliferation of endothelial cells are distinctive processes in the precursor and malignant lesions
of the uterine cervix. Activation of endothelial cells is an early stage that predominates in the
cervical intracellular lesions of the uterine cervix, while the endothelial proliferation is observed
in blood vessels of the invasive carcinomas. |
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