The scope of the research was to determine the biological efficiency of the microbiological product Paurin SC in the control of cherry brown rot (Monilia). Considering that during the ripening period of the fruits, falls abundant rainfall (end of May and June), which causes a strong development of fruit rot, the damage can exceed over 50% of production. the Application of chemical plant protection products are not allowed in this phase of fruit development. The use of microbiological products will allow to improve the environment and significantly reduce the use of chemical products and obviously to obtain secured productivity of ecologically pure fruits. Following the research, was found that the application of Paurin SC product against cherry Moniliosis (Monilia fructigena Pers.) keeps under control the spread and development of this disease during the ripening period of cherry fruits. In the climatic conditions of 2018 and 2019, the biological efficacy of Paurin SC with single treatment application constituted between 76.1-78.8% while the variant with two treatments reached an efficacy of 86.1 - 89.2%.