Propolis extracts from central zone of Moldova as an accessible and alternative therapeutic raw material
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638.17:615.324(478) (1)
Întreținerea, creșterea și utilizarea insectelor și a altor astropode (166)
Medicamentele potrivit originii lor (480)
SM ISO690:2012
POGREBNOI, Serghei, EREMIA, Nicolae, BILAN, Dmitri, LUPAŞCU, Lucian, BOLOCAN (SECARA), Natalia, DUKA, Gh., ARMAŞU, Svetlana, TERTEAC, Dumitru, CEBANU, Vitalie, TINCU, Serghei, ZNAGOVAN, Alexandru, MIHAILOVA (NEICOVCENA), Iulia, COȘELEVA, Olga, SLANINA, Valerina, MAKAEV, Fliur. Propolis extracts from central zone of Moldova as an accessible and alternative therapeutic raw material . In: Ecological and environmental chemistry : - 2022, Ed. 7, 3-4 martie 2022, Chișinău. Chisinau: Centrul Editorial-Poligrafic al USM, 2022, Ediția 7, Vol.1, p. 166. ISBN 978-9975-159-07-4.. 10.19261/eec.2022.v1
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Ecological and environmental chemistry
Ediția 7, Vol.1, 2022
Conferința "Ecological and environmental chemistry 2022"
7, Chișinău, Moldova, 3-4 martie 2022

Propolis extracts from central zone of Moldova as an accessible and alternative therapeutic raw material

CZU: 638.17:615.324(478)

Pag. 166-166

Pogrebnoi Serghei1, Eremia Nicolae2, Bilan Dmitri1, Lupaşcu Lucian1, Bolocan (Secara) Natalia1, Duka Gh.1, Armaşu Svetlana13, Terteac Dumitru13, Cebanu Vitalie3, Tincu Serghei4, Znagovan Alexandru4, Mihailova (Neicovcena) Iulia5, Coșeleva Olga5, Slanina Valerina6, Makaev Fliur1
 
1 Institute of Chemistry,
2 State Agrarian University of Moldova ,
3 Practical Scientific Institute of Horticulture and Food Technology,
4 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
5 Comrat State University,
6 Institute of Microbiology and Biotechnology
 
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Disponibil în IBN: 16 martie 2022


Rezumat

In the context of the Covid-19 coronavirus pandemic (SARS-CoV-2) situation, propolis was investigated, as an accessible and alternative therapeutic raw material, which rarely causes side effects. The results of the study of propolis extracts, collected in the central part of Moldova, showed that the nature of the solvent significantly affects the composition of the extracts, which differ in properties and can be recommended for the prevention of several diseases, including Covid-19. There were found 20 amino acids, of which the most abundant are glutamic acid, alanine, leucine and isoleucine. The main constituents of the alcoholic extract are pinocembrin, n-heptacosan and naringenin. The aqueous-alcoholic extract is characterized by the content of sakuranin, 4-methoxy sakuranetin, caryophylline oxide, isocaryophylline oxide, trans-longipinocarveol. Some components of the extracts, such as pinocembrine, have previously been proposed for the treatment of cerebral ischemia, intracerebral hemorrhage, neurodegenerative diseases, cardiovascular disease and atherosclerosis, also showing cardioprotective properties and a strong inhibitory effect on SARS-CoV-2 virus.