This study concerns the influence of a cianobacterial extract containing amino acids and oligopeptides on the growth, biomass and lipid accumulation, and quantitative and fractional lipid composition of Streptomyces canosus CNMN-Ac-02. The cyanobacterial extract was used as a supplement to growth liquid complex medium M-I. A significant increase of S. canosus CNMN-Ac-02 biomass yeld was registered for all concentrations in which the biological product was added. The best result was obtained using a concentration of 20.0 %/V of cyanobacterial extract, an increase by 81.38 % compared with control was recorded. Conversely, a larger amount of lipids (by 38.36 % compared with the control) was obtained using 0.1 %/V of cyanobacterial extract of amino acids and oligopeptides. Fraction of phospholipids in biomass of S. canosus CNMN-Ac-02 increased by 18.2 % - 25.39 % in comparison to the control, after cultivation on M-I medium with content of cyanobacterial extract of amino acids and oligopeptides, both in low concentrations (0.1-0.1 %/V). The cyanobacterial extract of amino acids and oligopeptides in concentration of 10.0-20.0 %/V, stimulate the accumulation of mono- and diglycerides by 8.91-16.2 % compared with the control. The fraction of sterols remained at the same level, but their esters increased by about 30 %.