Obtaining high-quality reproductive material from different species of animals is one of the most important problems of purposefully solving and preserving the animal species, improving the quantitative and qualitative indicators of the resulting products of different animal species, and it can also be predetermined as an important factor in the conservation of biodiversity. This article presents an analysis of the results of the review of specialized literature and experimental data obtained in our laboratory. As a result of the impact of external negative factors on the functioning of the reproductive system of males and the quality of reproductive material, it encourages specialists and researchers in this area to conduct additional comprehensive studies of the reproductive potential of males and to prevent the occurrence of such disorders at any level of organization of the functioning of the reproductive system and the quality of spermatogenesis. All these disorders lead to a lac