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Ultima descărcare din IBN: 2023-09-27 19:03 |
SM ISO690:2012 MUNTEANU, Oxana, SURLARI, Margarita, CEBOTARU, Aurelia, BOTNARU, Victor. A dilemma aprouch of pulmonary aspergillosis in a patient with ulcerative colitis and COVID-19. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 164. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | |||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | |||||
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Pag. 164-164 | |||||
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Rezumat | |||||
Background. COVID-19-associated pulmonary aspergillosis has been reported more frequently in patients with severe forms of SARS-CoV-2 infection, ARDS and invasive ventilation. Recognised as a new entity in the era of the COVID-19 pandemic, there are still a lot of diagnostic and management uncertainties. Objective of the study. To demonstrate a case of COVID-19-associated pulmonary aspergillosis in a patient without ARDS or mechanical invasive ventilation, but immunocompromised due to medication. Material and Methods. We present the clinical features, laboratory tests and the spectrum of radiological features that contribute to suspect the pulmonary aspergillosis associated with COVID-19 in a 68-year-old patient admitted for the haemoptysis and diarrhea, using for 15 years immunosuppressive therapies for ulcerative colitis. Results. The patient had no signs of a severe inflammatory syndrome during hospitalization for COVID (18 days), the ground glass opacities appeared on the 9th day of illness and evolved with small areas of bilateral consolidation. After discharge, high-dose systemic corticosteroids were given (20 days), but the cough intensified with occurrence of haemoptysis and diarrhea. Cavitary lesions identified on chest X-ray have progressed despite the antibacterial treatment. Chest HRCT revealed new areas of consolidation in the right upper lobe and a cavity with mycetoma in the left lower lobe. Clinical and imaging improvement were observed after voriconazole treatment. Conclusion. Aspergillosis should be suspected in cases of clinical deterioration or appearance of cavitary lesions, especially in immunocompromised patients with a history of high-dose corticosteroids or monoclonal antibodies therapy. |
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Cuvinte-cheie Aspergillosis, COVID-19, Colitis, aspergiloză, COVID-19, colită |
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