| Conţinutul numărului revistei |
| Articolul precedent |
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| Ultima descărcare din IBN: 2023-01-06 11:23 |
 SM ISO690:2012CONDREA, Alexandra, RĂCILĂ, Renata, DUARTE, Carolina , VASILIEVA, Maria, MANEA, Diana, GORINCIOI, Nadejda, CONDREA, Alexandra, CRIVORUCICA, Igor, ZOTA, Eremia, EFREMOVA, Daniela, CRIVORUCICA, Veaceslav, CIOCANU, Mihail, MOVILĂ, Alexandru, GROPPA, Stanislav. Clinical and radiological deterioration in a case of Creutzfeldt–Jakob disease following SARS-CoV-2 infection: Hints to accelerated age-dependent neurodegeneration. In: Biomedicines, 2021, vol. 9, p. 0. ISSN -. DOI: https://doi.org/10.3390/biomedicines9111730 |
| EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
  Biomedicines |
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| Volumul 9 / 2021 / ISSN - /ISSNe 2227-9059 | ||||||
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| DOI:https://doi.org/10.3390/biomedicines9111730 | ||||||
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Systemic inflammation and the host immune responses associated with certain viral infections may accelerate the rate of neurodegeneration in patients with Creutzfeldt–Jakob disease (CJD), a rare, transmissible neurodegenerative disease. However, the effects of the newly emerged SARS-CoV-2 infection on the pathogenesis of CJD are unknown. In this study, we describe the case of an elderly female patient with sporadic CJD that exhibited clinical deterioration with the emergence of seizures and radiological neurodegenerative progression following an infection with SARS-CoV-2 and severe COVID-19. Despite efforts to control the progression of the disease, a dismal outcome ensued. This report further evidences the age-dependent neurological effects of SARS-CoV-2 infection and proposes a vulnerability to CJD and increased CJD progression following COVID-19. |
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| Cuvinte-cheie Accelerated neurodegeneration, aging, Creutzfeldt–Jakob disease, SARS-CoV-2 |
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