Background and aims: Neonatal seizures are a common neurological dysfunction of the neonatal period, apparently from birth to the end of the neonatal period. The incidence of neonatal seizures is in range of 15/3 per 1/000 live births, in the neonatal period - with an index of 1.2. the evolution of neonatal seizures is often dependent on the cause that led to seizures. Methods: The results on the neurodevelopment of 67 newborn children who had neonatal seizures of various etiologies werw evaluated. Assessment period - 5 years. Examinations were performed: neurophysiological, imagistic. Results: Among the 67 children who had neonatal seizures during the newborn period, the following neurodevelopmental problems were registered: behavioral disorders (42 children, 63%), cognitive disorders (35 children, 53.7%), speech and language disorders (39 children, 58%), attention disorders (49 children, 73%), hyperactivity disorder (33 children, 49%), socializing disorders (31 children, 46%), epilepsy (20 children, 30%) , cerebral palsy (22 children, 33%), intellectual disability (19 children, 28%). Conclusion: Triggering causes of neonatal seizures determine long-term prognosis and outcomes, as they are associated with various brain injuries, can have a negative impact on the child’s neurodevelopmental outcomes. Disclosure: Nothing to disclose