Neurological manifestations in the late postoperative period in children operated with cerebelar astrocytoma
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616-008.9-036:616.831.7-006.4-089-053.2 (1)
Patologie. Medicină clinică (6963)
Neurologie. Neuropatologie. Sistem nervos (971)
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GRÎU, Corina, LITOVCENCO, Anatolii, CĂLCÎI, Cornelia, LUPUŞOR, Nadejda, CUZNETZ, Ludmila, FEGHIU, Leonid, SPRINCEAN, Mariana, LACUSTA, Victor, HADJIU, Svetlana. Neurological manifestations in the late postoperative period in children operated with cerebelar astrocytoma. In: European Journal of Neurology, 2021, nr. S1(28), p. 517. ISSN 1351-5101.
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European Journal of Neurology
Numărul S1(28) / 2021 / ISSN 1351-5101 /ISSNe 1468-1331

Neurological manifestations in the late postoperative period in children operated with cerebelar astrocytoma

CZU: 616-008.9-036:616.831.7-006.4-089-053.2

Pag. 517-517

Grîu Corina, Litovcenco Anatolii, Călcîi Cornelia, Lupuşor Nadejda, Cuznetz Ludmila, Feghiu Leonid, Sprincean Mariana, Lacusta Victor, Hadjiu Svetlana
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 14 noiembrie 2021


Rezumat

Background and aims: Cerebellar pilocytic astrocytoma is
the most common type of benign tumor located in the
cerebellum in children, and postoperative after-effects can
prevent recovery treatment, these children frequently need
care assistance.
Methods: Prospective study of late postoperative
neurological manifestations (≥ 2 years after intervention) in
14 children (aged 7–18 years) operated on with cerebellar
pilocytic astrocytoma between 2012–2018, who were not
subjected to radiotherapy or chemotherapy.
Results: The most affected age: 10–14 years (42.9%),
followed by 7–9 years (37.7%), then 14–18 years (21.4%).
Location in the cerebellum: vermis – 10 children, vermis
and both hemispheres – 1, right cerebellar hemisphere – 1,
left cerebellar hemisphere – two children. Postoperative
syndromes: posterior fossa – eight children (57.1% [II
60.33–44.17], p=0.05); moderate and severe motor deficit
– 10 (71.4%, [II 83.47–59.33], p=0.07), mild – one child;
expressive language deficit – five (35.7% [II 50.31–24.69],
p=0.05), spontaneous conversation – three (21.4%, [II
32.37–10.43], p=0.06). At the localization in the vermis
persisted the deficit of emotional control (anxiety, panic
attacks, aggression), as well as eating disorders – five
(35.7%); emotional lability – 12 (85.7%); cognitive
disorders – 12 (85.7%); vegetative disorders (bradycardia,
orthostatic syncope, hypotension, hyperhidrosis, flatulence,
asthenia, insomnia) – 12 (85.7%) children; and in the left
cerebellar hemisphere – dysmetry and dysdiadokokinesis.
Conclusion: In children operated on with cerebellar
astrocytoma in the postoperative period, neurological
manifestations with moderate and severe motor deficit
persist, as well as the symptoms of the vegetative nervous
system, negatively influencing their recovery.
Disclosure: Estimation of neurological manifestations in
the postoperative period in children operated on with
cerebellar pilocytic astrocytoma who have not undergone
radiotherapy or chemotherapy.