The study of current researches presents interest due to the frequency of cases recorded in some samples from various internal abscesses of slaughtered pigs, the assessment of identified bacterial microflora species and the determination of microbial species sensitivity to antibiotic substances. Microbiological researches of abscesses of different origins at slaughtered pigs has shown the presence of important bacterial microflora consisting of staphylococci, streptococci, E. coli, which plays a role in these pathologies, determining differentiated values according to all microbiological aspects. The bacterioscopic results of the bacterial microflora from the abscesses of the samples recorded high indices of microbial germs associated in number of 42 to the species of Staphylococcus, compared to the species of Streptococcus -31 and the species of E. coli -22 microorganisms. The evaluation of the bacterial microflora determined essential characteristics triggered by the Staphylococcus species, associated with the species frequently involved in the pathology of Streptococcus and E.coli abscesses. These research criteria are of interest by evaluating the behaviors of microbial species identified in swine abscess samples against different antibiotics, which led to the highlighting of important areas of antibiotic susceptibility, demonstrating various aspects of sensitivity and interpretation of virulence mechanisms in E.coli abscesses and other important strains noted in this study.