In the paper is described the mono- and poly-invasions impact on some morpho-functional indices in wild boars. So, in result of the investigation of hematological indices in uninfested mono- and poly-parasitized wild boars, it was established that both the indices of hemoglobin content, of hematocrit, erythrocyte’s number, thrombosis time and ESR (erythrocyte sedimentation rate) vary and are more increased in the I group with uninfested wild boars compared to mono - and poly-parasitized ones. It has been established that at infested boars with S. papillosus from the I group, and in those infested with D. lanceolatum from the II group there is a decrease of hemostatic indices, but their maximum decrease is highlighted in the IV group with wild boars infested with Dicrocoelium lanceolatum, Strongyloides papillosus, Metastrongylus elongatus and Eimeria debliecki. This decrease is due to eliminated exotoxins by parasites, which contain anticoagulants and hemolyzers and which neutralize the fibrinogen, thrombin, Ca+ ions and vitamin K properties from the body.