The article presents the results of studies of the relationship between measurements and milk production at Holstein cows of German and Dutch breeding in a herd of Joint-Stock Company „Aydyn”, Comrat, Administrative and Territorial Unit Gagauzia, Republic of Moldova. By the level of milk productivity, the cows of German breeding were significantly superior to cows of Dutch breeding by 507 kg of milk (II lactation, P<0.05) and 1529 kg of milk (III lactation, P<0.001), respectively. At cows of the Dutch breeding by the size of the milk yield and the connection with the measurements, dependence was found from the slightly negative −0.008 (metacarpus girth) to a high positive +0.665 (width in jobbers). The average milk yield relationship was established at cows of German breeding with a chest girth behind the shoulder blades (+0.364) and a width of a croup (+0.336), which indicates a positive dependence of milk production for carrying out breeding according to the size of exterior region.