Articolul precedent |
Articolul urmator |
907 18 |
Ultima descărcare din IBN: 2023-12-28 17:09 |
Căutarea după subiecte similare conform CZU |
547.814.1.07 (1) |
Chimie organică (484) |
SM ISO690:2012 BLAJA, Svetlana, ARICU, Aculina, KUCHKOVA, Kaleria, BARBA, Alic. Synthesis of some new homodrimane derivatives of benzothiazole from norambreinolide. In: New frontiers in natural product chemistry.: A destiny on the altar of research. Dedicated to academician Pavel Vlad, Ed. 6, 21 mai 2021, Chișinău. Chișinău, Republica Moldova: Tipografia "Artpoligraf", 2021, Ediția 6, p. 33. ISBN 978-9975-3336-7-2. DOI: https://doi.org/10.19261/nfnpc.2021.ab26 |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
New frontiers in natural product chemistry. Ediția 6, 2021 |
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Conferința " New frontiers in natural product chemistry." 6, Chișinău, Moldova, 21 mai 2021 | |||||||
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DOI:https://doi.org/10.19261/nfnpc.2021.ab26 | |||||||
CZU: 547.814.1.07 | |||||||
Pag. 33-33 | |||||||
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Many drimane and homodrimane sesquiterpenoids, including those containing nitrogen, are known to exhibit a variety of biological activities [1]. The search of new biologically active compounds prompted us to synthesize homodrimane sesquiterpenoids (4) and (6), containing benzothiazole fragment. Starting Δ8-bicyclohomofarnesoic acid (2) and Δ6,8-bicyclohomofarnesoic acid (5) were obtained from commercially available norambreinolide (1). Reaction of these acids with 2-aminothiophenole (3) produce 2-(Δ8-bicyclohomofarnesyl)-benzothiazole (4) and 2-(Δ6,8-bicyclohomofarnesyl)benzothiazole (6), accordingly. Reagents and conditions: a. Ph3P, Et3N, CCl4, Δ, 4 h. The structures of the newly obtained compounds were established on the basis of their spectral date (IR, 1H- and 13C-NMR, mass-spectra). |
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