This article discusses the impact of human-computer interaction in the pedagogical design of open textbooks affordable into a diversity of learning environments. An exploratory study is conducted, wherein an online questionnaire is administered to the second-year master’s degree students from the Faculty of Psychology and Educational Studies. The results show that students are aware of the importance of metacognition in developing effective learning strategies. Thus, they use metacognitive strategies when taking notes, doing reflections, and employing mnemonics to enhance understanding. However, despite the current practice of using open didactical materials, students feel that the open textbooks approach needs to be relooked and changed to be more effective; it could be equipped with appropriate learning tools to provide more opportunities for immediate feedback and collaborative assessment. Individualization and collaboration are the key factors in developing metacognitive experience. These findings indicate that students are cognizant of the important role of open textbooks in promoting learning.