Articolul precedent |
Articolul urmator |
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Ultima descărcare din IBN: 2023-11-24 17:06 |
SM ISO690:2012 OLEINIC, Vera, FRIPTU, Valentin, TOFAN-SCUTARU, Liudmila. Biomarkerii albuminei ischemic modificate şi autoanticorpii împotriva receptorului tip 1 angiotensinei II în predicția preeclampsiei. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 610. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||
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Pag. 610-610 | |||||
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Background. Ischemia modified albumin (IMA) biomarkers and angiotensin II type 1 receptor agonistic autoantibodies (AT1AA) are involved in the pathogenesis of preeclampsia, hypoxic ischemic status and oxidative stress in preeclampsia being associated with their increase. Objective of the study. Studying data from the literature on the role of IMA and AT1AA in predicting preeclampsia. Material and Methods. Searches were performed in the PubMed, Medline, Cochrane databases for studies published in 2015-2020, and included papers analyzing the role of IMA and AT1AA biomarkers in predicting preeclampsia, using the keywords: preeclampsia, IMA and AT1AA. Results. Analysis of recent studies showed that serum levels of AMI and AT1AA were significantly increased in preeclampsia. Elevated AT1AA values and a growth threshold over (56.84 ± 11.57 ng / ml) are reported for IMA associated with preeclampsia. Pathological changes in AT1AA and AMI, occurring in oxidative stress and endothelial dysfunction in preeclampsia, could mediate the development of cardiovascular disease and autoimmune processes later in life in women with preeclampsia. Conclusion. Increases in serum concentrations of AMI and AT1AA associated with preclampsia suggest that testing these biomarkers may be useful in predicting preeclampsia and the subsequent development of cardiovascular disease and autoimmune processes. |
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Cuvinte-cheie preeclampsia, IMA, AT1AA |
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