Articolul precedent |
Articolul urmator |
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SM ISO690:2012 STAMATI, Adela, REVENCO, Ninel. Impactul beta-blocantelor în tratamentul copiilor cu cardiomiopatie dilatativă. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 551. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 551-551 | ||||||
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Rezumat | ||||||
Background. Dilated cardiomyopathy (CMD) is the most common type of cardiomyopathy at any age. Incidence in children is 0.57-2.6 / 100,000 / year. The management of pediatric CMD is not similar to adults, the results of the combination of beta-blockers (BB) in the behavior of children with CMD is controversial. Objective of the study. The effects of beta-blockers in the clinical-hemodynamic evolution of children with CMD. Material and Method. The prospective analytical study included 48 children (age 3 months-18 years) with a clinical diagnosis of CMD. based on anamnestic criteria. clinical and imaging. Depending on the treatment, the patients were divided into 2 groups: I -14 children, conventional and BB; II - 34 children - conventional treatment. Statistical analysis through methods of variational, correlational and discriminant Results. Most of the children were young (58%), with a predominance of boys (M / F-30/18); 42 ptc (86%) presented ICC gr II-IV CF NYHA / Ross. Comparative analysis of EcoCg parameters determined marked cardiac dysfunction in both groups. Clinical evaluation and EcoCg of patients in group I improved in 1.5 months of surveillance. EcoCg parameters with non-perforable predictive value: Tei index, associated with LVEF, SIV thickness, PSAP and IVM grade. Unfavorable evolution in 6 children, including 4 deaths, of which 3 (8.82%) cases in group II. Adverse effects of BB - 1 case of hypotension and bradycardia. Conclusion. The Tei index is a predictor of death, depending on age and heart failure. The association of BB in the treatment of CMD in children in the early stages contributes to the clinical and functional improvement of the heart. Adverse effects are rare, requiring correct dose titration. |
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Cuvinte-cheie dilated cardiomyopathy, beta-blockers, prognosis, cardiomiopatie dilatativă, betablocante, prognostic |
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