Articolul precedent |
Articolul urmator |
317 3 |
Ultima descărcare din IBN: 2023-11-24 11:58 |
SM ISO690:2012 RUSSU, Dumitru. Abcesul pulmonar în infecția COVID 19. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 443. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||
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Pag. 443-443 | |||||
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Rezumat | |||||
Background. Severe acute respiratory syndrome, produced by SARS-CoV-2, exerts a significant global impact, causing severe challenges in society and healthcare. Empirical data on how patients with various respiratory pathologies interact with this virus are limited. Objective of the study. To evaluate the impact of SARS-CoV-2 infection on the immune system, as well as the susceptibility of SARS-CoV-2 infection in patients with active or antecedents of lung abscess (LA), in order to interpret its clinical significance. Material and Methods. Using Google Scholar search engine and the PubMed, Research for Life și Medline databases, advanced literature search was conducted. Article selection criteria included the immune system’s response in COVID-19 infection in patients with respiratory pathology, including lung abscess. 24 articles published up to 25 May 2020 were selected. Results. Various mechanisms of SARS-CoV-2 infection and COVID-19 immunopathogenesis have been unraveled in the context of lung abscess patients. The control of the inflammatory response may be as important as controlling viremia. Treatment of viral inhibition and the regulation of hyper- or hypoergic immune responses may act synergistically to stop the progression of the disease in several pathogenetic links. Further studies are needed on the host immune response to SARS-CoV-2, in the context of chronic or acute suppurative lung disease, including a detailed investigation on determining factors in this regard. Conclusion. Patients with a history of LA present a higher susceptibility to SARS-CoV-2 infection due to impairment in nonspecific and specific immune elements, the deterioration of vascular architectonics and poor oxygenation in the post-abscess scar region, and lifestyle. |
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Cuvinte-cheie lung abscess, immune response, SARS-CoV-2, COVID 19, abces pulmonar, răspuns imun, SARS-CoV-2, COVID 19 |
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